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      Our R&D Capabilities

      Medix Biochemica’s scientific professionals have decades of experience on the development of essential raw materials for diagnostic applications. With 1 of 4 employees dedicated to design and development of new products, we are able to keep up with the cutting-edge of all aspects of the IVD industry — from native and recombinant antibodies and antigens to molecular diagnostic reagents. Our customer-centric approach makes us the ideal partner to meet your needs. Our R&D and analytical teams also utilize their expertise to develop assay methods, purification schemes, and tailor or scale up processes to deliver the right product and solutions for our clients’ final application. Please get in touch with us today to discuss your bespoke needs.

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      Monoclonal antibody development

      Medix Biochemica has been a pioneer in monoclonal antibody development since the late 1970’s. We have world-leading expertise in developing novel antibodies for all types of molecules relevant in IVD, both with mouse hybridoma and phage display technologies. Our R&D professionals also have thorough knowledge and experience on the adaptation of antibody-producing cell lines to industrial scale animal-free manufacturing processes.

      State-of-the-art recombinant technologies are also used in our product development department to develop engineered antibodies. We rescue antibodies from hybridomas to recombinant form and switch the domains between different species when needed. We analyze antibody structures computationally and engineer them for enhanced performance, to ensure our customers will have the best options available for their IVD tests.

      Native Proteins
      Native Proteins
      Our R&D team has unique experience on the development of fully scalable processes for the purification of native proteins from a range of different animal and human materials. A wide spectrum of extraction and chromatography methods are used to develop enrichment and purification protocols for native enzymes, antigens, and other proteins, also in situations where the natural abundance of the target protein is very low in the original source material.
      Recombinant Proteins
      Recombinant Proteins
      We develop recombinant proteins for calibrator and control products, or for use as critical raw materials in serological tests. Both bacterial and mammalian expression hosts are used, for optimal expression and functionality.
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      Molecular Diagnostic Reagents
      Our experienced R&D team works on the development of a broad range of molecular reagents, such as unique, engineered polymerases and master mixes that enable a wide range of molecular biology applications.
      Protein Analytics
      Protein Analytics
      Monoclonal antibodies, native, and recombinant proteins are carefully characterized with a comprehensive selection of analytical tools in our R&D laboratories. The biochemical and functional properties are studied by various chromatographic, electrophoretic, enzymatic, immunochemical, cytometric, and kinetic analyses.